Tablets of mosapride citrate and preparation method thereof



The invention belongs to the field of medicaments and in particular relates to tablets containing mosapride citrate and a preparation method thereof. Because the mosapride citrate is almost insoluble, defects of slow dissolution and low in-vitro and in-vivo bioavailability are present in the mosapride citrate tablets prepared by the common method. In order to improve the dissolution and bioavailability of the mosapride citrate, the invention provides dispersible tablets containing the mosapride citrate and a preparation method thereof. The prepared mosapride citrate dispersible tablets have high dissolution speed and low dissolution difference. The accumulated dissolution in five minutes is close to 100 percent, and the dispersible tablets are almost dissolved completely.




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Cited By (6)

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    CN-102600091-AJuly 25, 2012威海迪素制药有限公司, 迪沙药业集团山东迪沙药业有限公司, 迪沙药业集团有限公司Itopride hydrochloride dispersible tablet composition
    CN-104188927-ADecember 10, 2014鲁南制药集团股份有限公司Mosapride citrate tablet and preparation method thereof
    CN-104546686-AApril 29, 2015南京工业大学Mosapride citrate co-grinded product, preparation method thereof and medicine composition containing mosapride citrate co-grinded product
    CN-104546686-BDecember 01, 2017南京百思福医药科技有限公司一种枸橼酸莫沙必利共研磨物及其制备方法和含其药物组合物
    CN-104622826-AMay 20, 2015孙巧玲一种枸橼酸莫沙必利片剂及其制备方法
    CN-105560249-AMay 11, 2016成都康弘药业集团股份有限公司一种含有枸橼酸莫沙必利的药物组合物